Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.67 |
| ▸ | ITGA2 | P17301 | 4/20 | 0.67 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.67 |
| ▸ | CCR4 | P51679 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254342 | 0.93 | ITGB1 (0.77) | ITGB1ITGA2ITGA4CCR4LMNA | |
| SCHEMBL8248907 | 0.93 | ITGB1 (0.77) | ITGB1ITGA2ITGA4CCR4LMNA | |
| SCHEMBL8248434 | 0.90 | ITGB1 (0.72) | ITGB1ITGA2ITGA4FKBP1AMMP2 | |
| SCHEMBL8238713 | 0.90 | ITGB1 (0.69) | ITGB1ITGA2ITGA4FKBP1AMMP2 | |
| SCHEMBL8244932 | 0.88 | ITGB1 (0.74) | ITGB1ITGA2ITGA4HPGDFKBP1A | |
| SCHEMBL8249029 | 0.87 | ITGB1 (0.71) | ITGB1ITGA2ITGA4FKBP1A | |
| SCHEMBL8246392 | 0.87 | ITGB1 (0.71) | ITGB1ITGA2ITGA4FKBP1A | |
| SCHEMBL8246168 | 0.87 | ITGB1 (0.65) | ITGB1ITGA2ITGA4FKBP1AMMP2 | |
| SCHEMBL12084502 | 0.83 | ITGB1 (0.83) | ITGB1ITGA2ITGA4FKBP1AMMP2 | |
| SCHEMBL8239058 | 0.83 | ITGB1 (0.83) | ITGB1ITGA2ITGA4FKBP1AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006133338-A1 | INHIBITORS OF THE α2β1/GPIa-IIa INTEGRIN | THE TRUSTEES OF THE UNIVERSITY OF PENNESYLVANIA (US) | 2006-12-14 | — | — | WO | disclosed |