Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.64 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8245612 | 0.90 | ADORA2A (0.73) | ADORA2AIRAK4 | |
| SCHEMBL8249497 | 0.89 | ADORA2A (0.80) | ADORA2A | |
| SCHEMBL14156103 | 0.88 | ADORA2A (0.83) | ADORA2A | |
| SCHEMBL8247550 | 0.83 | ADORA2A (0.70) | ADORA2A | |
| SCHEMBL8249551 | 0.82 | ADORA2A (0.72) | ADORA2A | |
| SCHEMBL8246886 | 0.82 | ADORA2A (0.55) | ADORA2AIRAK4SMN1; SMN2 | |
| SCHEMBL8246979 | 0.80 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL4590424 | 0.79 | ADORA2A (0.92) | ADORA2A | |
| SCHEMBL8246929 | 0.78 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL4590042 | 0.78 | ADORA2A (1.00) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022305-A2 | 2-AMINOIMIDAZOPYRIDINES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |