⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306158 | 1.00 | — | — | |
| SCHEMBL8427705 | 1.00 | — | — | |
| SCHEMBL383530 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5038885 | 0.98 | MEN1 (0.36) | — | |
| SCHEMBL21166045 | 0.80 | MEN1 (0.34) | — | |
| SCHEMBL21166066 | 0.80 | MEN1 (0.34) | — | |
| SCHEMBL21166099 | 0.80 | MEN1 (0.34) | — | |
| SCHEMBL24981342 | 0.76 | MEN1 (0.34) | — | |
| SCHEMBL19881546 | 0.76 | MEN1 (0.34) | — | |
| SCHEMBL23583672 | 0.76 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701689-B2 | Substituted pyridines and pyridazines as CCR10 receptor inhibitors | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-07-11 | — | — | US | disclosed |
| US-9701689-B2 | Substituted pyridines and pyridazines as CCR10 receptor inhibitors | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-07-11 | — | — | US | disclosed |
| US-20150299214-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150299214-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
| WO-2008077809-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| US-20080154043-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | US | disclosed |
| US-20080154043-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | US | disclosed |