Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560948 | 0.93 | HDAC1 (0.64) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL5560952 | 0.93 | HDAC1 (0.64) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL8249424 | 0.91 | HDAC1 (0.68) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5565623 | 0.90 | HDAC1 (0.78) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5565621 | 0.90 | HDAC1 (0.78) | HDAC1HDAC8HDAC6 | |
| SCHEMBL8252857 | 0.88 | HDAC1 (0.69) | HDAC1HDAC8HDAC6ESR1ESR2 | |
| SCHEMBL8249069 | 0.87 | HDAC1 (0.82) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5565817 | 0.84 | HDAC1 (0.61) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5565813 | 0.84 | HDAC1 (0.61) | HDAC1HDAC8HDAC6 | |
| SCHEMBL8250741 | 0.84 | HDAC1 (0.61) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169801-B2 | Histone deacetylase inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040266769-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266769-A1 | Histone deacetylase inhibitors | HDAC1, HDAC11, HDAC10 | HDAC1 1/4885HDAC8 10/4885HDAC6 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.