Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 7/20 | 0.59 |
| ▸ | ITGA2 | P17301 | 4/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253387 | 0.94 | ITGB1 (0.68) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL12084495 | 0.94 | ITGB1 (0.68) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL8244929 | 0.92 | ITGB1 (0.55) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL8238713 | 0.92 | ITGB1 (0.69) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL4251535 | 0.90 | ITGB1 (0.73) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL8245510 | 0.90 | ITGB1 (0.73) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL8248434 | 0.88 | ITGB1 (0.72) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL8245644 | 0.87 | ITGB1 (0.64) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL8248234 | 0.86 | ITGB1 (0.65) | ITGB1ITGA2ITGA4MMP2MMP9 | |
| SCHEMBL4260308 | 0.86 | ITGB1 (0.65) | ITGB1ITGA2ITGA4MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006133338-A1 | INHIBITORS OF THE α2β1/GPIa-IIa INTEGRIN | THE TRUSTEES OF THE UNIVERSITY OF PENNESYLVANIA (US) | 2006-12-14 | — | — | WO | disclosed |