Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.74 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.74 |
| ▸ | CDK4 | P11802 | 1/20 | 0.74 |
| ▸ | CCND1 | P24385 | 1/20 | 0.74 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.74 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.64 |
| ▸ | CDK9 | P50750 | 1/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.63 |
| ▸ | PRKCA | P17252 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30319849 | 0.86 | CCNE2 (1.00) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL5686048 | 0.86 | CCNE2 (1.00) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL3775416 | 0.80 | GSK3B (0.79) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL5333204 | 0.80 | CDK2 (0.71) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL6950992 | 0.80 | GSK3B (0.94) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL8162217 | 0.79 | CDK2 (0.83) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL8804764 | 0.78 | CCNE2 (0.82) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL8167092 | 0.78 | CDK2 (0.76) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL30319850 | 0.77 | GSK3B (1.00) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL8161830 | 0.77 | CCNE2 (0.81) | CDK2CCNE2CDK4CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008514-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | GEORGETOWN UNIVERSITY (US) | 2007-01-18 | — | — | WO | disclosed |