Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.63 |
| ▸ | ITK | Q08881 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246817 | 0.98 | ADORA2A (0.60) | ADORA2AITK | |
| SCHEMBL4590485 | 0.91 | ADORA2A (0.63) | ADORA2AITKMEN1MAPK1KMT2A | |
| SCHEMBL4590479 | 0.91 | ADORA2A (0.63) | ADORA2AITKMEN1MAPK1KMT2A | |
| SCHEMBL14156188 | 0.90 | ADORA2A (0.78) | ADORA2AITK | |
| SCHEMBL8246937 | 0.88 | ADORA2A (0.60) | ADORA2AITK | |
| SCHEMBL8247560 | 0.87 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL14156090 | 0.87 | ADORA2A (0.75) | ADORA2AITK | |
| SCHEMBL8239534 | 0.87 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL8246609 | 0.87 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL8246362 | 0.87 | ADORA2A (0.57) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022305-A2 | 2-AMINOIMIDAZOPYRIDINES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |