Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.77 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.77 |
| ▸ | ITGB7 | P26010 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810176 | 0.89 | ITGB1 (0.77) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413023 | 0.87 | ITGB1 (1.00) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2846067 | 0.86 | ITGB1 (0.74) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2608705 | 0.85 | ITGB1 (0.65) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2845984 | 0.84 | ITGB1 (0.71) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2846113 | 0.84 | ITGB1 (0.71) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413074 | 0.84 | ITGB1 (0.87) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2843451 | 0.84 | ITGB1 (0.72) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413087 | 0.84 | ITGB1 (0.86) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413011 | 0.84 | ITGB1 (0.82) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041324-A1 | CARBAMATE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2007-04-12 | — | — | WO | disclosed |