SCHEMBL825181

SCHEMBL825181

CCCCCCCCCCCCCCCCCCN(CCN(Cc1ccccn1)Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
MAPT P10636 1/20 0.69
LIN28A Q9H9Z2 1/20 0.69
TERT O14746 1/20 0.46
NR1H2 P55055 1/20 0.44
NR1H3 Q13133 1/20 0.44
CXCR4 P61073 2/20 0.44
KCNH2 Q12809 2/20 0.43
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM5 P08912 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
KDM4E B2RXH2 3/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.41
KCNA5 P22460 2/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825403 1.00 TDP1 (0.69) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL1332466 1.00 TDP1 (0.69) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL135635 0.97 TDP1 (0.68) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL1051354 0.97 TDP1 (0.68) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL29898520 0.97 TDP1 (0.68) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL29402044 0.97 TDP1 (0.68) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL27681560 0.97 TDP1 (0.62) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL15177847 0.97 TDP1 (0.68) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL230599 0.95 TDP1 (0.70) TDP1SMN1; SMN2MAPTLIN28ATERT
SCHEMBL846457 0.94 TDP1 (0.73) TDP1SMN1; SMN2MAPTLIN28ATERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US claimed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US claimed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP claimed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US claimed
US-8642685-B2 Liquid hardening OMG UK Technology, Ltd (GB) 2014-02-04 US claimed
US-20130123452-A1 CURING LIQUIDS OMG ADDITIVES LIMITED (UK) 2013-05-16 US claimed
US-20130041079-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2013-02-14 US claimed
EP-2521750-A1 CURING LIQUIDS OMG Additives Limited (GB) 2012-11-14 EP claimed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO claimed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP claimed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP claimed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US claimed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 US disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 US disclosed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 EP disclosed
WO-2020142632-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA, Inc. (US) 2020-07-09 WO disclosed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP disclosed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP disclosed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US disclosed
EP-2103735-A1 Catalytic bleaching of substrates Unilever PLC (GB) 2009-09-23 EP disclosed