SCHEMBL8252759

SCHEMBL8252759

CN1CCc2ccc(NC(=O)C(CC3CCCCC3)NC(=O)c3ccc(Cl)s3)cc2CC1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 16/20 0.45
PPM1D O15297 2/20 0.44
F2RL1 P55085 1/20 0.41
USP30 Q70CQ3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2571662 1.00 F10 (0.45) F10PPM1DF2RL1USP30
SCHEMBL13069897 0.90 PPM1D (0.41) F10PPM1DF2RL1USP30
SCHEMBL2568468 0.86 NPC1 (0.38) PPM1DF2RL1USP30
SCHEMBL3031666 0.86 F10 (0.58) F10
SCHEMBL3028076 0.85 F10 (0.48) F10
SCHEMBL2568218 0.85 F10 (0.60) F10
SCHEMBL3032269 0.85 F10 (0.59) F10
SCHEMBL3033197 0.85 F10 (0.48) F10
SCHEMBL3031307 0.85 F10 (0.51) F10
SCHEMBL3023945 0.85 F10 (0.51) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007003536-A1 SUBSTITUTED GLYCINAMIDES HAVING AN ANTITHROMBOTIC AND FACTOR XA-INHIBITING EFFECT BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-01-11 WO disclosed