Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257468 | 1.00 | F10 (1.00) | F10 | |
| SCHEMBL8256840 | 0.92 | F10 (1.00) | F10 | |
| SCHEMBL8260028 | 0.92 | F10 (1.00) | F10 | |
| SCHEMBL8259652 | 0.92 | F10 (0.86) | F10 | |
| SCHEMBL8250861 | 0.92 | F10 (0.84) | F10 | |
| SCHEMBL8250903 | 0.92 | F10 (1.00) | F10 | |
| SCHEMBL3451494 | 0.91 | F10 (0.83) | F10 | |
| SCHEMBL8251696 | 0.91 | F10 (1.00) | F10 | |
| SCHEMBL8258213 | 0.91 | F10 (0.83) | F10 | |
| SCHEMBL13110533 | 0.90 | F10 (0.82) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| WO-2006114401-A2 | NOVEL CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | WO | disclosed |