Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252924 | 0.93 | PDE5A (0.74) | PDE5APDE6A | |
| SCHEMBL8251732 | 0.92 | PDE5A (0.70) | PDE5APDE6A | |
| SCHEMBL8255251 | 0.92 | PDE5A (0.70) | PDE5APDE6A | |
| SCHEMBL8250697 | 0.89 | PDE5A (0.81) | PDE5APDE6A | |
| SCHEMBL8253985 | 0.89 | PDE5A (0.73) | PDE5APDE6A | |
| SCHEMBL8255169 | 0.88 | PDE5A (0.73) | PDE5APDE6A | |
| SCHEMBL8250217 | 0.88 | PDE5A (0.81) | PDE5APDE6A | |
| SCHEMBL8253787 | 0.88 | PDE5A (0.81) | PDE5APDE6A | |
| SCHEMBL8254215 | 0.88 | PDE5A (0.81) | PDE5APDE6A | |
| SCHEMBL8245619 | 0.87 | PDE5A (0.72) | PDE5APDE6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006126081-A2 | PYRIDINO [2 , 3-B] PYRAZINONES AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-11-30 | — | — | WO | disclosed |