Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275631 | 0.86 | MCL1 (0.65) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL7981184 | 0.85 | MCL1 (0.62) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL29945775 | 0.82 | MCL1 (0.70) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL15657021 | 0.82 | MCL1 (0.70) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL117186 | 0.81 | MCL1 (1.00) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL14723647 | 0.80 | MCL1 (0.57) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8600262 | 0.79 | MCL1 (0.96) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL16599480 | 0.78 | MCL1 (0.76) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL27467673 | 0.78 | MCL1 (0.74) | MCL1SLC9A1KMT2AMAPTMEN1 | |
| SCHEMBL401039 | 0.77 | MCL1 (0.73) | MCL1SLC9A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435407-B1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RAQUALIA PHARMA INC (JP) | 2019-12-25 | — | — | EP | disclosed |
| WO-2007006714-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |