Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256495 | 0.85 | HDAC1 (0.63) | HDAC1HDAC8 | |
| SCHEMBL8253751 | 0.78 | HDAC1 (0.73) | HDAC1HDAC8 | |
| SCHEMBL8257306 | 0.76 | HDAC1 (0.77) | HDAC1HDAC8 | |
| SCHEMBL3369062 | 0.76 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL3369058 | 0.76 | HDAC1 (1.00) | HDAC1HDAC8 | |
| SCHEMBL8258947 | 0.72 | HDAC1 (0.60) | HDAC1HDAC8 | |
| SCHEMBL3372830 | 0.72 | HDAC1 (0.93) | HDAC1HDAC8 | |
| SCHEMBL3372833 | 0.72 | HDAC1 (0.93) | HDAC1HDAC8 | |
| SCHEMBL8289364 | 0.72 | HDAC1 (0.82) | HDAC1HDAC8 | |
| SCHEMBL3369380 | 0.69 | HDAC1 (1.00) | HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101456-A1 | BICYCLIC HETEROCYCLES HYDROXAMATE COMPOUNDS USEFUL AS HISTONE DEACETYLASE (HDAC) INHIBITORS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |