Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.52 |
| ▸ | F3 | P13726 | 20/20 | 0.52 |
| ▸ | F10 | P00742 | 13/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 11/20 | 0.51 |
| ▸ | F11 | P03951 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14009540 | 0.94 | F7 (0.58) | F7F3F10PRSS1PRSS2 | |
| SCHEMBL4999984 | 0.80 | F7 (0.60) | F7F3F10PRSS1PRSS2 | |
| SCHEMBL6089721 | 0.79 | F7 (0.78) | F7F3F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL2848764 | 0.78 | F7 (0.77) | F7F3F10PRSS1PRSS2 | |
| SCHEMBL4657710 | 0.77 | F7 (0.48) | F7F3F10PRSS1PRSS2 | |
| SCHEMBL2853487 | 0.76 | F7 (0.56) | F7F3F10PRSS1PRSS2 | |
| SCHEMBL8234975 | 0.76 | F7 (0.57) | F7F3F10PRSS1PRSS2 | |
| SCHEMBL4657711 | 0.75 | F7 (0.46) | F7F3F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL5882854 | 0.75 | F10 (0.85) | F7F3F10PRSS1PRSS2 | |
| SCHEMBL8253736 | 0.75 | NR1H4 (0.37) | F7F3F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002313-A2 | PHENYLGLYCINAMIDE AND PYRIDYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |