Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251893 | 0.93 | PDE5A (0.66) | PDE5APDE6A | |
| SCHEMBL8245549 | 0.86 | PDE5A (0.90) | PDE5APDE6A | |
| SCHEMBL8251641 | 0.85 | PDE5A (0.71) | PDE5APDE6A | |
| SCHEMBL8243988 | 0.76 | PDE5A (0.73) | PDE5APDE6A | |
| SCHEMBL8244023 | 0.76 | PDE5A (1.00) | PDE5APDE6A | |
| SCHEMBL8250192 | 0.76 | PDE5A (0.68) | PDE5APDE6A | |
| SCHEMBL6073255 | 0.76 | PDE5A (0.74) | PDE5APDE6A | |
| SCHEMBL8243769 | 0.75 | PDE5A (0.64) | PDE5APDE6A | |
| SCHEMBL8253965 | 0.74 | PDE5A (0.65) | PDE5APDE6A | |
| SCHEMBL8251469 | 0.74 | PDE5A (0.85) | PDE5APDE6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006126081-A2 | PYRIDINO [2 , 3-B] PYRAZINONES AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-11-30 | — | — | WO | disclosed |