Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4161705 | 0.89 | F10 (0.44) | F10ESR2NR1H2 | |
| SCHEMBL8257648 | 0.87 | F10 (0.43) | F10ESR2NR1H2 | |
| SCHEMBL4170302 | 0.86 | F10 (0.44) | F10ESR2NR1H2 | |
| SCHEMBL4929296 | 0.85 | F10 (0.45) | F10 | |
| SCHEMBL4170624 | 0.83 | F10 (0.66) | F10ESR2 | |
| SCHEMBL4172923 | 0.82 | F10 (0.63) | F10 | |
| SCHEMBL4176222 | 0.82 | F10 (0.63) | F10 | |
| SCHEMBL4183584 | 0.80 | F10 (0.43) | F10ESR2NR1H2 | |
| SCHEMBL4176488 | 0.80 | F10 (0.39) | F10ESR2NR1H2 | |
| SCHEMBL4926935 | 0.79 | F10 (0.67) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006108709-A1 | 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-10-19 | — | — | WO | disclosed |