SCHEMBL8256758

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27700648	0.85	PTPN1 (0.61)	PTPN1KDM4EHTTGSK3BKMT2A
	SCHEMBL84296	0.75	PTPN1 (0.50)	PTPN1HTTGSK3BKMT2AMAOA
	SCHEMBL12830182	0.75	—	—
	SCHEMBL19099914	0.75	CYP3A4 (0.46)	KMT2AMAOAMAOBMEN1
	SCHEMBL31231895	0.75	PTPN1 (0.50)	PTPN1KDM4EHTTGSK3BKMT2A
	SCHEMBL23330765	0.75	PTPN1 (0.50)	PTPN1KDM4EHTTGSK3BKMT2A
	SCHEMBL2090321	0.75	PTPN1 (0.50)	PTPN1KDM4EHTTGSK3BKMT2A
	SCHEMBL718267	0.75	PTPN1 (0.50)	PTPN1KDM4EHTTGSK3BKMT2A
	SCHEMBL31231900	0.75	PTPN1 (0.50)	PTPN1KDM4EHTTGSK3BKMT2A
	SCHEMBL20274093	0.75	PTPN1 (0.50)	PTPN1KDM4EHTTGSK3BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.