Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 15/20 | 0.68 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.68 |
| ▸ | PSMB8 | P28062 | 6/20 | 0.68 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.68 |
| ▸ | PSMB10 | P40306 | 6/20 | 0.68 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.68 |
| ▸ | ELANE | P08246 | 2/20 | 0.68 |
| ▸ | CTSG | P08311 | 2/20 | 0.68 |
| ▸ | CMA1 | P23946 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | LONP1 | P36776 | 8/20 | 0.54 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934804 | 1.00 | PSMB5 (0.68) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL2934071 | 0.87 | PSMB5 (0.73) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL2936700 | 0.85 | PSMB5 (0.68) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL3164355 | 0.85 | PSMB5 (0.67) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL2927894 | 0.84 | PSMB5 (0.70) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL8259864 | 0.82 | PSMB5 (0.64) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL2933648 | 0.82 | PSMB5 (0.64) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL24195078 | 0.82 | PSMB5 (0.78) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL2933926 | 0.82 | PSMB5 (0.78) | PSMB5PSMB1PSMB8PSMB9PSMB10 | |
| SCHEMBL2930837 | 0.82 | PSMB5 (0.72) | PSMB5PSMB1PSMB8PSMB9PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086600-A1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2006-08-17 | — | — | WO | disclosed |