Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.56 |
| ▸ | FNTA | P49354 | 12/20 | 0.53 |
| ▸ | FNTB | P49356 | 12/20 | 0.53 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985868 | 0.83 | CYP11B1 (0.61) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL5891635 | 0.80 | CYP11B1 (0.57) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7484730 | 0.78 | CYP11B1 (0.62) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8531142 | 0.75 | CYP11B1 (0.59) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8191731 | 0.74 | CYP11B1 (0.73) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8534308 | 0.74 | CYP11B1 (0.58) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8413422 | 0.74 | BRS3 (0.47) | — | |
| SCHEMBL7477932 | 0.73 | FNTA (0.56) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8095394 | 0.73 | FNTA (0.60) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL2786255 | 0.73 | CYP11B1 (0.71) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
| US-5922883-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-07-13 | — | — | US | disclosed |