Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12715066 | 0.97 | TDP1 (0.54) | TDP1TP53HSD17B1HSD17B2PTGS2 | |
| SCHEMBL14548354 | 0.92 | TP53 (0.59) | TDP1TP53HSD17B1HSD17B2PTGS2 | |
| SCHEMBL12858352 | 0.92 | TDP1 (0.59) | TDP1TP53NPC1CASP3SENP8 | |
| SCHEMBL2602506 | 0.92 | TDP1 (0.50) | TDP1TP53HSD17B1HSD17B2PTGS2 | |
| SCHEMBL12084044 | 0.90 | TP53 (0.66) | TDP1TP53HSD17B1HSD17B2PTGS2 | |
| SCHEMBL5196214 | 0.90 | TDP1 (0.44) | TDP1TP53PTGS2TSHRALDH1A1 | |
| SCHEMBL16247990 | 0.89 | TDP1 (0.47) | TDP1TP53PTGS2NPC1NR1H4 | |
| SCHEMBL12757056 | 0.89 | TDP1 (0.47) | TDP1TP53HSD17B1HSD17B2PTGS2 | |
| SCHEMBL766100 | 0.89 | TDP1 (0.47) | TDP1TP53HSD17B1HSD17B2PTGS2 | |
| SCHEMBL12858654 | 0.89 | TP53 (0.63) | TDP1TP53HSD17B1HSD17B2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588527-B1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | NISSAN CHEMICAL IND LTD (JP) | 2017-10-25 | — | — | EP | disclosed |
| US-20170186953-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-29 | — | — | US | disclosed |
| US-20170186953-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-29 | — | — | US | disclosed |
| US-9577194-B2 | Hole transport compositions and related devices and methods (I) | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| US-9577194-B2 | Hole transport compositions and related devices and methods (I) | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| US-8815639-B2 | Hole transport compositions and related devices and methods (II) | SOLVAY USA, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815639-B2 | Hole transport compositions and related devices and methods (II) | SOLVAY USA, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8535974-B2 | Hole transport compositions and related devices and methods (II) | PLEXTRONICS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8535974-B2 | Hole transport compositions and related devices and methods (II) | PLEXTRONICS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-20120003790-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AMD METHODS (II) | PLEXTRONICS, INC. | 2012-01-05 | — | — | US | disclosed |
| US-20120003790-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AMD METHODS (II) | PLEXTRONICS, INC. | 2012-01-05 | — | — | US | disclosed |
| US-20120001127-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | PLEXTRONICS, INC. | 2012-01-05 | — | — | US | disclosed |
| US-20120001127-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | PLEXTRONICS, INC. | 2012-01-05 | — | — | US | disclosed |
| WO-2012003485-A2 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | PLEXTRONICS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012003482-A2 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (II) | PLEXTRONICS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120001127-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | OCIAD2, OCIAD1, SLCO1B1 | TDP1 3356/4885TP53 4548/4885HSD17B1 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.