Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260790 | 0.89 | NR3C2 (0.43) | NR3C2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8260792 | 0.87 | NR3C2 (0.42) | NR3C2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13587741 | 0.78 | NR3C2 (0.58) | NR3C2KDM4E | |
| SCHEMBL13587768 | 0.76 | NR3C2 (0.56) | NR3C2KDM4E | |
| SCHEMBL13587771 | 0.76 | NR3C2 (0.56) | NR3C2KDM4E | |
| SCHEMBL13587767 | 0.76 | NR3C2 (0.56) | NR3C2TBXA2RSLC6A3KCNH2CACNA1C | |
| SCHEMBL13587756 | 0.71 | KDM4E (0.51) | NR3C2TBXA2RALOX15ADORA3SCN5A | |
| SCHEMBL8258936 | 0.71 | NR3C2 (0.51) | NR3C2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7431518 | 0.70 | CACNA1C (0.53) | NR3C2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8259167 | 0.70 | KDM4E (0.54) | NR3C2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066011-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | IRM LLC (BM) | 2006-06-22 | — | — | WO | disclosed |