Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 17/20 | 0.74 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.73 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.69 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.63 |
| ▸ | PSMD11 | O00231 | 4/20 | 0.63 |
| ▸ | PSMD12 | O00232 | 4/20 | 0.63 |
| ▸ | PSMD14 | O00487 | 4/20 | 0.63 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.63 |
| ▸ | PSMD3 | O43242 | 4/20 | 0.63 |
| ▸ | PSMC3 | P17980 | 4/20 | 0.63 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.63 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.63 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.63 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.63 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.63 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.63 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.63 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.63 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.63 |
| ▸ | PSMC2 | P35998 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13079074 | 1.00 | PSMB5 (0.74) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL8259345 | 0.91 | PSMB5 (0.65) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL8250540 | 0.90 | PSEN1 (0.66) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL13529856 | 0.90 | PSMB5 (0.88) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL8257602 | 0.89 | PSMB5 (0.64) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL8251426 | 0.89 | PSMB5 (0.64) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL8257625 | 0.89 | PSEN1 (0.62) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL10243656 | 0.89 | PSMB5 (0.69) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL13079064 | 0.88 | PSMB5 (0.63) | PSMB5PSMB1PSMB2PSMB11PSMD11 | |
| SCHEMBL8257914 | 0.88 | PSEN1 (0.61) | PSMB5PSMB1PSMB2PSMB11PSMD11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086600-A1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2006-08-17 | — | — | WO | disclosed |