⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353265 | 0.69 | — | — | |
| SCHEMBL10706828 | 0.67 | — | — | |
| SCHEMBL1524653 | 0.64 | — | — | |
| SCHEMBL11832661 | 0.61 | — | — | |
| SCHEMBL5405411 | 0.61 | — | — | |
| SCHEMBL10707556 | 0.58 | — | — | |
| SCHEMBL6672103 | 0.58 | — | — | |
| SCHEMBL54268 | 0.57 | — | — | |
| SCHEMBL19279012 | 0.57 | — | — | |
| SCHEMBL11093062 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576505-A1 | PROCESS FOR THE PREPARATION OF PLEUROMUTILINS | Nabriva Therapeutics AG (AT) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011146954-A1 | PROCESS FOR THE PREPARATION OF PLEUROMUTILINS | NABRIVA THERAPEUTICS AG (AT) | 2011-12-01 | — | — | WO | disclosed |