Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 7/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 5/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201788 | 0.89 | IRAK4 (0.51) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1202079 | 0.87 | MAOB (0.53) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1201724 | 0.87 | IRAK4 (0.47) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1201005 | 0.86 | IRAK4 (0.57) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL9611644 | 0.85 | MAOB (0.48) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1202142 | 0.84 | IRAK4 (0.50) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1201877 | 0.84 | PKN1 (0.47) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1201653 | 0.83 | PARP1 (0.49) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1202155 | 0.83 | MAOB (0.46) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL1200975 | 0.83 | MAOB (0.45) | MAOBADORA2AADORA2BADORA1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099379-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS B-SECRETASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2006-09-21 | — | — | WO | disclosed |