Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285393 | 0.91 | TP53 (0.38) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3285964 | 0.90 | TP53 (0.42) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3286834 | 0.89 | TP53 (0.41) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3284580 | 0.88 | TP53 (0.42) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL8261092 | 0.87 | TP53 (0.41) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3286715 | 0.85 | TP53 (0.44) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3284505 | 0.85 | TP53 (0.44) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3284178 | 0.84 | TP53 (0.48) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3285286 | 0.84 | TP53 (0.47) | TP53LMNAPOLBALDH1A1HPGD | |
| SCHEMBL3284611 | 0.84 | TP53 (0.47) | TP53LMNAPOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006089909-A1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-08-31 | — | — | WO | disclosed |