Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 15/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 15/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550517 | 0.83 | ALOX5AP (0.53) | FEN1ALOX5AP | |
| SCHEMBL481771 | 0.81 | ALOX5AP (0.51) | FEN1ALOX5APFYN | |
| SCHEMBL2644580 | 0.78 | ALOX5AP (0.68) | FEN1ALOX5AP | |
| SCHEMBL13729541 | 0.76 | KDM1A (0.52) | FEN1ALOX5AP | |
| SCHEMBL6075271 | 0.74 | ALOX5AP (0.53) | FEN1ALOX5AP | |
| SCHEMBL6703514 | 0.73 | ALOX5AP (0.52) | FEN1ALOX5APFYNPDE10A | |
| SCHEMBL15915519 | 0.73 | ALOX5AP (0.56) | FEN1ALOX5AP | |
| SCHEMBL6074984 | 0.72 | ALOX5AP (0.48) | FEN1ALOX5AP | |
| SCHEMBL1702391 | 0.72 | ALOX5AP (0.45) | FEN1ALOX5AP | |
| SCHEMBL15205210 | 0.69 | FEN1 (0.46) | FEN1ALOX5APPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081391-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-03 | — | — | WO | disclosed |