Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694805 | 0.84 | RXFP1 (0.58) | HCRTR1RXFP1KMT2ACA1CA2 | |
| SCHEMBL14560536 | 0.82 | RXFP1 (0.57) | HCRTR1RXFP1KMT2ACA1CA2 | |
| SCHEMBL1856372 | 0.81 | CYP1A2 (0.65) | KMT2ACYP1A2CYP2C19TSHR | |
| SCHEMBL4021415 | 0.81 | RXFP1 (0.57) | HCRTR1RXFP1KMT2ACA1CA2 | |
| SCHEMBL4021338 | 0.81 | RXFP1 (0.57) | HCRTR1RXFP1CA1CA2LMNA | |
| SCHEMBL11872791 | 0.77 | CYP1A2 (0.59) | HCRTR1RXFP1KMT2ACA1CA2 | |
| SCHEMBL4796690 | 0.77 | CYP1A2 (0.58) | KMT2ACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL20854901 | 0.75 | TDP1 (0.58) | KMT2ACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL21616881 | 0.75 | TDP1 (0.58) | KMT2ACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL9850718 | 0.74 | HCRTR1 (0.62) | HCRTR1RXFP1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524823-B2 | Macrolides | BASILEA PHARMACEUTICA AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-7524823-B2 | Macrolides | BASILEA PHARMACEUTICA AG (CH) | 2009-04-28 | — | — | US | disclosed |
| EP-1846430-B1 | NEW MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2009-04-01 | — | — | EP | disclosed |
| WO-2006084410-A1 | NEW MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2006-08-17 | — | — | WO | disclosed |