Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.78 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | F11 | P03951 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258146 | 0.88 | F10 (1.00) | F10 | |
| SCHEMBL13110326 | 0.82 | F10 (0.62) | F10F2 | |
| SCHEMBL5432357 | 0.81 | F10 (0.76) | F10F2F11 | |
| SCHEMBL5630650 | 0.81 | F10 (0.76) | F10F2F11 | |
| SCHEMBL5630655 | 0.81 | F10 (0.76) | F10F2F11 | |
| SCHEMBL8258241 | 0.81 | F10 (1.00) | F10 | |
| SCHEMBL3447943 | 0.78 | F10 (0.85) | F10 | |
| SCHEMBL3447938 | 0.78 | F10 (0.85) | F10 | |
| SCHEMBL8257259 | 0.78 | F10 (1.00) | F10 | |
| SCHEMBL8255935 | 0.78 | F10 (1.00) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |
| WO-2006114401-A2 | NOVEL CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | WO | disclosed |