Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC27A1 | Q6PCB7 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260111 | 0.83 | F10 (0.51) | F10ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL13110503 | 0.83 | F10 (0.55) | F10ALDH1A1LMNASLC27A1RAB9A | |
| SCHEMBL13110278 | 0.74 | F10 (0.55) | F10ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8258187 | 0.70 | F10 (0.55) | F10ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8251764 | 0.69 | F10 (0.52) | F10ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL3447166 | 0.69 | F10 (0.50) | F10ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3447170 | 0.69 | F10 (0.50) | F10ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8257332 | 0.69 | F10 (1.00) | F10 | |
| SCHEMBL8257336 | 0.69 | F10 (1.00) | F10 | |
| SCHEMBL3448527 | 0.68 | KMT2A (0.58) | F10ALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006114401-A2 | NOVEL CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | WO | disclosed |