Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806239 | 0.81 | DPP4 (0.57) | DPP4DPP9DPP8FAP | |
| SCHEMBL5806233 | 0.81 | DPP4 (0.57) | DPP4DPP9DPP8FAP | |
| SCHEMBL5819747 | 0.79 | DPP4 (0.51) | DPP4DPP9DPP8FAPDPP7 | |
| SCHEMBL2847016 | 0.71 | DPP4 (0.47) | DPP4DPP9DPP8FAPDPP7 | |
| SCHEMBL13025325 | 0.71 | DPP4 (0.47) | DPP4DPP9DPP8FAP | |
| SCHEMBL6375288 | 0.70 | DPP4 (1.00) | DPP4DPP9DPP8FAP | |
| SCHEMBL5820282 | 0.67 | DPP4 (0.68) | DPP4DPP9DPP8FAP | |
| SCHEMBL8261998 | 0.67 | DPP4 (0.68) | DPP4DPP9DPP8FAP | |
| SCHEMBL5585963 | 0.66 | DPP4 (0.73) | DPP4DPP9DPP8FAP | |
| SCHEMBL2871206 | 0.66 | DPP4 (0.73) | DPP4DPP9DPP8FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006090244-A1 | NEW ADAMANTANE DERIVATIVES AS DIPEPTIDYL, PEPTIDASE IV INHIBITORS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-08-31 | — | — | WO | disclosed |