⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977616 | 0.74 | — | — | |
| SCHEMBL18772784 | 0.71 | — | — | |
| SCHEMBL13348722 | 0.71 | — | — | |
| SCHEMBL473678 | 0.71 | — | — | |
| SCHEMBL22180010 | 0.69 | — | — | |
| SCHEMBL9296847 | 0.67 | — | — | |
| SCHEMBL14598241 | 0.67 | — | — | |
| SCHEMBL8212715 | 0.67 | — | — | |
| SCHEMBL10284116 | 0.67 | — | — | |
| SCHEMBL15506179 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221665-A1 | Organic Compounds | EARNEST DAVID LEWIS | 2009-09-03 | — | — | US | disclosed |
| US-20090221665-A1 | Organic Compounds | EARNEST DAVID LEWIS | 2009-09-03 | — | — | US | disclosed |
| US-20080269311-A1 | Combination of Dpp-Iv Inhibitors and Compounds Modulating 5-Ht3 and/or 5-Ht4 Receptors | VILLHAUER EDWIN BERNARD | 2008-10-30 | — | — | US | disclosed |
| US-20080269311-A1 | Combination of Dpp-Iv Inhibitors and Compounds Modulating 5-Ht3 and/or 5-Ht4 Receptors | VILLHAUER EDWIN BERNARD | 2008-10-30 | — | — | US | disclosed |
| US-20080161307-A1 | Administering a 5-HT4 agonist, e.g. tegaserod; Proton Pump Inhibitor-induced delayed gastric emptying | NOVARTIS AG (CH) | 2008-07-03 | — | — | US | disclosed |
| US-20080161307-A1 | Administering a 5-HT4 agonist, e.g. tegaserod; Proton Pump Inhibitor-induced delayed gastric emptying | NOVARTIS AG (CH) | 2008-07-03 | — | — | US | disclosed |
| WO-2006083710-A2 | USE OF 5-HT4 AGONIST FOR TREATING DELAYED GASTRIC EMPTYING WHICH MAY BE INDUCED BY A PROTON PUMP INHIBITOR | NOVARTIS AG (CH) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006005613-A1 | COMBINATION OF DPP-IV INHIBITORS AND COMPOUNDS MODULATING 5-HT3 AND/OR 5-HT4 RECEPTORS | NOVARTIS AG (CH) | 2006-01-19 | — | — | WO | disclosed |