Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821588 | 1.00 | HDAC1 (0.52) | HDAC1TSHRALDH1A1ANPEPMAPT | |
| SCHEMBL5808394 | 0.90 | HDAC1 (0.61) | HDAC1ANPEPKDM1A | |
| SCHEMBL8255875 | 0.90 | HDAC1 (0.61) | HDAC1ANPEPKDM1A | |
| SCHEMBL5809262 | 0.90 | HDAC1 (0.59) | HDAC1TSHRALDH1A1 | |
| SCHEMBL8260764 | 0.90 | HDAC1 (0.59) | HDAC1TSHRALDH1A1 | |
| SCHEMBL8257525 | 0.89 | HDAC1 (0.55) | HDAC1ANPEPKDM1A | |
| SCHEMBL5805067 | 0.89 | HDAC1 (0.55) | HDAC1ANPEPKDM1A | |
| SCHEMBL5805396 | 0.85 | HDAC1 (0.55) | HDAC1ANPEPKDM1A | |
| SCHEMBL8254245 | 0.85 | HDAC1 (0.55) | HDAC1ANPEPKDM1A | |
| SCHEMBL5823705 | 0.85 | HDAC1 (0.62) | HDAC1ANPEPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |