Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604999 | 0.86 | IDO1 (0.45) | DPP4DPP8DPP9CNR1CNR2 | |
| SCHEMBL1408253 | 0.83 | DPP4 (0.55) | DPP4DPP8DPP9IDO1MAPT | |
| SCHEMBL1408229 | 0.82 | DPP4 (0.66) | DPP4DPP8DPP9 | |
| SCHEMBL1408226 | 0.81 | DPP4 (0.69) | DPP4DPP8DPP9CNR1CNR2 | |
| SCHEMBL1407927 | 0.79 | CNR1 (0.46) | DPP4DPP8DPP9CNR1CNR2 | |
| SCHEMBL13605001 | 0.78 | DPP4 (0.49) | DPP4DPP8DPP9IDO1MAPT | |
| SCHEMBL1408313 | 0.77 | DPP4 (0.49) | DPP4DPP8DPP9CNR1CNR2 | |
| SCHEMBL1408083 | 0.74 | DPP4 (0.55) | DPP4DPP8DPP9CNR1CNR2 | |
| SCHEMBL1407903 | 0.73 | DPP4 (0.47) | DPP4DPP8DPP9CNR1CNR2 | |
| SCHEMBL1408216 | 0.73 | DPP4 (0.47) | DPP4DPP8DPP9CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006071752-A1 | AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |