Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260711 | 0.88 | NR3C2 (0.62) | NR3C2CYP1A2CYP3A4ADORA3MAPT | |
| SCHEMBL8259588 | 0.87 | NR3C2 (0.62) | NR3C2MAPTTSHR | |
| SCHEMBL13587784 | 0.86 | NR3C2 (0.46) | NR3C2CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL8260833 | 0.83 | NR3C2 (0.47) | NR3C2 | |
| SCHEMBL8261160 | 0.81 | NR3C2 (0.50) | NR3C2 | |
| SCHEMBL8259769 | 0.80 | NR3C2 (0.48) | NR3C2 | |
| SCHEMBL8259186 | 0.80 | NR3C2 (0.49) | NR3C2 | |
| SCHEMBL3812166 | 0.80 | HTT (0.43) | NR3C2CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL13587737 | 0.79 | NR3C2 (0.49) | NR3C2MAPTTSHRKMT2A | |
| SCHEMBL8258517 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066011-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | IRM LLC (BM) | 2006-06-22 | — | — | WO | disclosed |