Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.72 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259289 | 0.95 | HDAC1 (0.68) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL8260503 | 0.93 | HDAC1 (0.64) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL5287405 | 0.93 | HDAC1 (0.62) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL5280493 | 0.91 | HDAC1 (0.60) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL5280487 | 0.91 | HDAC1 (0.60) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL8261388 | 0.87 | HDAC1 (0.78) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL5326792 | 0.86 | HDAC1 (0.71) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL5326785 | 0.86 | HDAC1 (0.71) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL5278245 | 0.86 | HDAC1 (0.55) | HDAC1HDAC4HDAC6MEF2DEP300 | |
| SCHEMBL5281071 | 0.85 | ANPEP (0.53) | HDAC1HDAC4HDAC6MEF2DEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |