Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 14/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 14/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 11/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201166 | 0.86 | NAMPT (0.46) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL1202167 | 0.85 | MAPK8 (0.45) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL1201825 | 0.84 | MAPK8 (0.45) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL1201420 | 0.83 | NAMPT (0.44) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL1201728 | 0.82 | NAMPT (0.42) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL1201708 | 0.82 | HDAC3 (0.45) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL1201849 | 0.76 | HDAC3 (0.42) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL1201673 | 0.75 | HDAC3 (0.41) | NAMPTCYP2C9HDAC3HDAC1HDAC2 | |
| SCHEMBL9611680 | 0.75 | HDAC3 (0.38) | HDAC3HDAC1HDAC2MAPK8MAPK9 | |
| SCHEMBL1201985 | 0.73 | KCNQ3 (0.43) | NAMPTCYP2C9HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099379-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS B-SECRETASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2006-09-21 | — | — | WO | disclosed |