SCHEMBL8262

SCHEMBL8262

c1ccc2c(c1)CCOC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
HTR2C P28335 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAOB P27338 5/20 0.36
CYP2A6 P11509 1/20 0.36
PNMT P11086 1/20 0.36
CD44 P16070 1/20 0.36
MAOA P21397 4/20 0.34
DRD2 P14416 1/20 0.34
DRD1 P21728 1/20 0.34
DRD4 P21917 1/20 0.34
DRD5 P21918 1/20 0.34
DRD3 P35462 1/20 0.34
LMNA P02545 2/20 0.33
CRHBP P24387 2/20 0.33
CRHR2 Q13324 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385689 1.00 TSHR (0.46) TSHRHTR2CCA12CA1CA2
SCHEMBL28695844 0.97 TSHR (0.43) TSHRHTR2CCA12CA1CA2
Hydrochloric Acid SCHEMBL7397054 0.97 TSHR (0.43) TSHRHTR2CCA12CA1CA2
Ammonia Solution, Strong SCHEMBL10744703 0.97 TSHR (0.43) TSHRHTR2CCA12CA1CA2
SCHEMBL28685927 0.91 TSHR (0.39) TSHRHTR2CCA12CA1CA2
Acetone SCHEMBL8527947 0.87 NOTUM (0.42) TSHRCA12CA1CA2CA9
Phenol SCHEMBL29229001 0.87 CA12 (0.44) TSHRHTR2CCA12CA1CA2
SCHEMBL2062312 0.86 TSHR (0.53) TSHRHTR2CCA12CA1CA2
SCHEMBL3994216 0.85 SMN1; SMN2 (0.43) TSHRMAOBMAOALMNACRHBP
SCHEMBL30387832 0.85 TSHR (0.55) TSHRHTR2CCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8868 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
EP-4678634-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Haihe Biopharma Co., Ltd. (CN) 2026-01-14 EP claimed
WO-2025133657-A1 BIARYL-TYPE HETEROCYCLIC COMPOUNDS AND ANTI-BACTERIAL USES THEREOF DEBRECENI EGYETEM (HU) 2025-06-26 WO claimed
CN-119264096-A Preparation method of isochromanone compound 辽宁石油化工大学 2025-01-07 CN claimed
CN-118754890-A Isochroman spiro pyrazolone compound and preparation method thereof 天津科技大学 2024-10-11 CN claimed
WO-2024193313-A1 ISOCHROMANE COMPOUNDS AS WELL AS PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 江苏联环药业股份有限公司 2024-09-26 WO claimed
EP-3494119-B1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA INC (US) 2024-09-04 EP claimed
US-20240239792-A1 MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF ASIA VISION LIMITED (CN) 2024-07-18 US claimed
CN-118344324-A Isochroman-1-ketone compound, preparation method and application thereof 江苏海洋大学 2024-07-16 CN claimed
CN-112512529-B Cyclopentenepurine derivative or salt thereof 富士胶片株式会社 2024-06-18 CN claimed
US-4241157-A ORGANIC PIGMENTS CONTAINING PYRIMIDINE RING EASTMAN KODAK COMPANY (US) 1980-12-23 US claimed
EP-0005652-A2 Electrophoretic migration imaging process and dispersion EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-11-28 EP claimed
EP-0004914-A1 Process for the production of compounds useful in perfumery INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-10-31 EP claimed
US-4166740-A CYANINE DYES EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed
US-4165985-A PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS EASTMAN KODAK COMPANY (US) 1979-08-28 US claimed
US-4162256-A Process for the production of compounds useful in perfumery INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-07-24 US claimed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US claimed
EP-0000599-A1 Electrically photosensitive particles for photoelectrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
EP-0000596-A1 Electrically photosensitive particles for electrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
US-3978090-A Process for production of isochromans INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-08-31 US claimed