Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.67 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12187043 | 0.83 | DPP4 (0.65) | DPP4DPP8DPP9 | |
| SCHEMBL8255595 | 0.83 | DPP4 (0.65) | DPP4DPP8DPP9 | |
| SCHEMBL8261997 | 0.83 | DPP4 (0.43) | DPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5207185 | 0.80 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6166027 | 0.80 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| SCHEMBL5802541 | 0.74 | DPP4 (0.80) | DPP4DPP8DPP9 | |
| SCHEMBL465003 | 0.74 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| SCHEMBL5805098 | 0.74 | DPP4 (0.80) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5207169 | 0.74 | DPP4 (0.98) | DPP4DPP8DPP9 | |
| SCHEMBL3928203 | 0.73 | DPP4 (0.78) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006090244-A1 | NEW ADAMANTANE DERIVATIVES AS DIPEPTIDYL, PEPTIDASE IV INHIBITORS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-08-31 | — | — | WO | disclosed |