Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 7/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219744 | 1.00 | CDK2 (0.50) | CDK2CCNA2CDK1CCNB1CHEK1 | |
| SCHEMBL16995287 | 0.94 | CDK2 (0.45) | CDK2CCNA2CDK1CCNB1CHEK1 | |
| SCHEMBL8261337 | 0.89 | CCNA2 (0.57) | CDK2CCNA2CDK1CCNB1ADORA2A | |
| SCHEMBL8219257 | 0.88 | CDK2 (0.56) | CDK2CCNA2CDK1CCNB1CCNA1 | |
| SCHEMBL8219161 | 0.88 | CCNA2 (0.63) | CDK2CCNA2CDK1CCNB1CCNA1 | |
| SCHEMBL8296007 | 0.83 | CDK2 (0.50) | CDK2CCNA2CDK1CCNB1CHEK1 | |
| SCHEMBL12000432 | 0.83 | CDK2 (0.66) | CDK2CCNA2CDK1CCNB1CHEK1 | |
| SCHEMBL1286717 | 0.83 | CDK2 (0.66) | CDK2CCNA2CDK1CCNB1CHEK1 | |
| SCHEMBL8228035 | 0.83 | CCNA2 (0.55) | CDK2CCNA2ADORA2AADORA1CNR1 | |
| SCHEMBL13543788 | 0.83 | CCNA2 (0.48) | CDK2CCNA2CDK1CCNB1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006077424-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |