Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.52 |
| ▸ | PDE4A | P27815 | 18/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL72328 | 0.99 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL8321734 | 0.87 | PDE4D (0.55) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL84494 | 0.83 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL8264976 | 0.81 | PDE4D (0.59) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL73785 | 0.81 | PDE4D (0.49) | PDE4DPDE4APDE4BPDE4CGFER | |
| Hydrochloric Acid SCHEMBL74596 | 0.81 | PDE4D (0.58) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL15016191 | 0.79 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL84964 | 0.78 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CGFER | |
| Hydrochloric Acid SCHEMBL74285 | 0.78 | PDE4D (0.59) | PDE4DPDE4APDE4BPDE4CGFER | |
| SCHEMBL73163 | 0.78 | MKNK1 (0.46) | PDE4DPDE4APDE4BPDE4CGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831227-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-06-19 | — | — | EP | claimed |
| EP-1831227-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-06-19 | — | — | EP | disclosed |
| WO-2006064355-A2 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-06-22 | — | — | WO | disclosed |