Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88815 | 0.85 | KMT2A (0.62) | MEN1KMT2ASMPD1TP53CYP1A2 | |
| SCHEMBL31053926 | 0.85 | MAPK1 (0.63) | MEN1KMT2ASMPD1TP53PDE4B | |
| SCHEMBL88998 | 0.85 | CA12 (0.67) | SMPD1TP53PDE4BPRSS1 | |
| SCHEMBL2438091 | 0.85 | PDE4D (0.53) | SMPD1TP53PDE4BPRSS1 | |
| SCHEMBL15202688 | 0.84 | MAPK1 (0.67) | MEN1KMT2AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL29578705 | 0.84 | MEN1 (0.73) | MEN1KMT2AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL515746 | 0.84 | MEN1 (0.73) | MEN1KMT2AKDM4ESMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL3372494 | 0.84 | CA12 (0.65) | SMPD1TP53PDE4BPRSS1 | |
| SCHEMBL56262 | 0.84 | MAPT (0.60) | MEN1KMT2ASMPD1KDM4ETP53 | |
| SCHEMBL2937932 | 0.84 | SMPD1 (0.56) | MEN1KMT2ASMPD1TP53PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066896-A2 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2006-06-29 | — | — | WO | disclosed |