Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 9/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263164 | 0.90 | IL2 (0.51) | IL2MAPK14F10 | |
| SCHEMBL4766180 | 0.80 | IL2 (0.52) | IL2ABL1MAPK14 | |
| SCHEMBL12093754 | 0.78 | IL2 (0.53) | IL2ABL1MAPK14KCNQ3KCNQ2 | |
| SCHEMBL8261670 | 0.76 | ABL1 (0.50) | IL2ABL1MAPK14 | |
| SCHEMBL8261669 | 0.75 | IL2 (0.51) | IL2MAPK14 | |
| SCHEMBL8261688 | 0.72 | IL2 (0.57) | IL2MAPK14F10 | |
| SCHEMBL4770091 | 0.72 | IL2 (0.52) | IL2 | |
| SCHEMBL16456568 | 0.72 | STIM1 (0.49) | IL2ABL1MAPK14 | |
| SCHEMBL4762886 | 0.71 | IL2 (0.48) | IL2ABL1MAPK14 | |
| SCHEMBL4762822 | 0.71 | IL2 (0.60) | IL2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083477-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-10 | — | — | WO | disclosed |