Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 12/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762822 | 0.85 | IL2 (0.60) | IL2MAPK14MEN1KMT2ATNF | |
| SCHEMBL8261688 | 0.84 | IL2 (0.57) | IL2MAPK14MEN1KMT2ATNF | |
| SCHEMBL8263163 | 0.82 | IL2 (0.53) | IL2MAPK14MEN1KMT2ATNF | |
| SCHEMBL4769885 | 0.81 | IL2 (0.65) | IL2MAPK14MEN1KMT2ANPC1 | |
| SCHEMBL8261674 | 0.80 | IL2 (0.52) | IL2MAPK14MEN1KMT2ATNF | |
| SCHEMBL16471116 | 0.79 | IL2 (0.57) | IL2MAPK14MEN1KMT2A | |
| SCHEMBL1828207 | 0.79 | IL2 (0.63) | IL2MEN1KMT2ATNFSTIM1 | |
| SCHEMBL8263164 | 0.78 | IL2 (0.51) | IL2MAPK14MEN1KMT2ATNF | |
| SCHEMBL8261669 | 0.78 | IL2 (0.51) | IL2MAPK14MEN1KMT2ATNF | |
| SCHEMBL8261672 | 0.78 | IL2 (0.52) | IL2MAPK14MEN1KMT2ATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083477-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-10 | — | — | WO | disclosed |