Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8262377 | 0.92 | PDE5A (0.85) | PDE5AKCNH2 | |
| SCHEMBL8243114 | 0.90 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL5245548 | 0.90 | PDE5A (0.83) | PDE5AKCNH2 | |
| SCHEMBL8261484 | 0.89 | PDE5A (0.80) | PDE5AKCNH2 | |
| SCHEMBL12768844 | 0.88 | PDE5A (0.84) | PDE5AKCNH2 | |
| SCHEMBL4466349 | 0.88 | PDE5A (0.83) | PDE5AKCNH2 | |
| SCHEMBL8261476 | 0.88 | PDE5A (0.79) | PDE5AKCNH2 | |
| SCHEMBL8236323 | 0.88 | PDE5A (0.78) | PDE5AKCNH2 | |
| SCHEMBL4039868 | 0.86 | PDE5A (0.84) | PDE5AKCNH2 | |
| SCHEMBL8261473 | 0.86 | PDE5A (0.75) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006046135-A2 | PYRAZOLO[4,3-D] PYRIMIDINE DERIVATIVES USEFUL AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-05-04 | — | — | WO | disclosed |