Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535952 | 0.91 | HDAC1 (0.82) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL3535280 | 0.90 | HDAC1 (0.69) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL3534742 | 0.90 | HDAC1 (0.69) | HDAC1HDAC2HDAC11HDAC8HDAC6 | |
| SCHEMBL3534226 | 0.88 | HDAC1 (0.67) | HDAC1HDAC2HDAC11HDAC8HDAC6 | |
| SCHEMBL3536813 | 0.88 | HDAC1 (0.69) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL3537402 | 0.88 | HDAC1 (0.66) | HDAC1HDAC8HDAC6 | |
| SCHEMBL3538578 | 0.86 | HDAC1 (0.69) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL3532266 | 0.86 | HDAC1 (0.69) | HDAC1HDAC2HDAC11HDAC8HDAC6 | |
| SCHEMBL3535258 | 0.84 | HDAC1 (0.64) | HDAC1HDAC2HDAC3NCOR1HDAC8 | |
| SCHEMBL3535597 | 0.84 | HDAC1 (0.67) | HDAC1HDAC2HDAC11HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066133-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-06-22 | — | — | WO | disclosed |