Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | NCOR1 | O75376 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064336 | 0.81 | HDAC1 (0.76) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL1064069 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL1064400 | 0.76 | HDAC1 (0.70) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL1083540 | 0.72 | HDAC1 (0.67) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL210812 | 0.72 | HDAC1 (0.79) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL2414954 | 0.72 | HDAC1 (0.69) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL10814316 | 0.72 | HDAC1 (0.59) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL15518884 | 0.72 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL2413506 | 0.71 | HDAC1 (0.68) | HDAC1HDAC3HDAC2NCOR2HDAC8 | |
| SCHEMBL8348463 | 0.71 | HDAC1 (0.83) | HDAC1HDAC3HDAC2NCOR2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066133-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-06-22 | — | — | WO | disclosed |