Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 14/20 | 0.77 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16482992 | 0.87 | FFAR4 (1.00) | FFAR4 | |
| SCHEMBL2560547 | 0.83 | FFAR4 (0.78) | FFAR4ADRB1KCNH2ALDH1A1MAPT | |
| SCHEMBL2557268 | 0.83 | FFAR4 (0.61) | FFAR4NOTUMMAPT | |
| SCHEMBL26373077 | 0.82 | FFAR4 (0.55) | FFAR4GPR119MAPT | |
| SCHEMBL5800964 | 0.81 | NOTUM (0.83) | FFAR4NOTUMGPR119ADRB1KCNH2 | |
| SCHEMBL2558104 | 0.80 | NOTUM (0.56) | FFAR4NOTUMGPR119ADRB1KCNH2 | |
| SCHEMBL7015829 | 0.78 | FFAR4 (0.50) | FFAR4 | |
| SCHEMBL23731860 | 0.77 | NOTUM (0.59) | FFAR4NOTUMGPR119ADRB1KCNH2 | |
| SCHEMBL31381256 | 0.77 | NOTUM (0.68) | FFAR4NOTUMGPR119ADRB1KCNH2 | |
| SCHEMBL17427966 | 0.77 | KCNH2 (0.61) | FFAR4NOTUMADRB1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177518-A1 | Organic compounds | Novartis AG (CH) | 2010-04-21 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |