Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ASF1A | Q9Y294 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132258 | 0.83 | GAA (0.55) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL1132257 | 0.83 | GAA (0.55) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL8264527 | 0.83 | MAPT (0.56) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL8265093 | 0.81 | MAPT (0.60) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL1132108 | 0.78 | GAA (0.52) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL1132110 | 0.78 | GAA (0.52) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL1132534 | 0.76 | GAA (0.63) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL1132532 | 0.76 | GAA (0.63) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL30495458 | 0.73 | KMT2A (0.69) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL12218406 | 0.72 | KMT2A (0.65) | KMT2AMAPTKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006029850-A1 | HYDRAZONE DERIVATIVES AND THEIR USE AS BETA SECRETASE INHIBITORS | THE GENETICS COMPANY, INC. (CH) | 2006-03-23 | — | — | WO | disclosed |