Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TACR3 | P29371 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363718 | 0.90 | TACR3 (0.43) | ADORA2AADORA1SLC2A1TACR3 | |
| SCHEMBL8265727 | 0.87 | ADORA2A (0.40) | ADORA2AADORA1TLR7SLC2A1MAPT | |
| SCHEMBL4357027 | 0.79 | TACR3 (0.46) | ADORA2AADORA1SLC2A1TACR3TDP1 | |
| SCHEMBL4361680 | 0.78 | TACR3 (0.45) | ADORA2AADORA1SLC2A1TACR3TDP1 | |
| SCHEMBL4358870 | 0.76 | TACR3 (0.43) | ADORA2AADORA1SLC2A1MAPTTACR3 | |
| SCHEMBL3038770 | 0.73 | TACR3 (0.46) | TLR7SLC2A1MAPTTACR3MEN1 | |
| SCHEMBL4351001 | 0.71 | TACR3 (0.38) | SLC2A1MAPTTACR3MEN1KMT2A | |
| SCHEMBL3030178 | 0.71 | SLC2A1 (0.43) | TLR7SLC2A1MAPTTACR3SMN1; SMN2 | |
| SCHEMBL8263391 | 0.71 | GAA (0.49) | ADORA2AADORA1SLC2A1TACR3KDM4E | |
| SCHEMBL4352784 | 0.70 | TACR3 (0.42) | ADORA2AADORA1SLC2A1MAPTTACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067430-A1 | 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |